Kidsquash Completes 8th Season with Smiles | Tariq Mohammed's ...

March 30, 2013 ? 11:21 pm

Since the 2004 pilot of Kidsquash, we marked the completion of the 8^thKidsquash season with ten students from the Greater Boston community. They played in a friendly round robin under the supervision of Laura Gemmell, a Harvard senior and 4-time All-American on the women?s varsity squash team, Octavio Chiesa, a volunteer peer coach and myself.

Beginner junior squash players make progress at Kidsquash.

From October 2012 to March 2013, Kidsquash students gathered for Saturday morning recreational squash clinics. Thanks to donations from the Harvard Athletics Department, we were able to recognize 4 students who are newcomers to the sport with Harvard squash apparel. These students were ? Megan Yoh (Best Female Player), Seamus Buckley (Most Improved Player), Will Gladstone (Most Valuable Player) and Samuel Esquivel (Sportsmanship Award).

Many thanks to Luke Hammond, Lead Coach for Kidsquash , Mike Way, Head Squash Coach at Harvard and Coach Bajwa, Founder of Kidsquash for their guidance and support of the program. Also, thank you to Kidsquash parents and sponsors for making it a great season!

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Source: http://tariqmohammed.wordpress.com/2013/03/30/kidsquash-completes-8th-season-with-smiles/

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Oncolytics lung cancer drug effective in mid-stage trial, shares up

(Reuters) - Oncolytics Biotech Inc said its experimental lung cancer drug was found to be more effective in a mid-stage trial study, sending its shares up more than 10 percent.

Shares of the Calgary-based biotechnology company rose to a high of C$3.32 on the Toronto Stock Exchange on Thursday.

The main goal was to see if nine or more patients had a partial or better response to the treatment in the second stage trial, which studied 36 patients.

The endpoint was met after 21 patients were treated. Nine of them showed partial response, while another nine showed stable disease and three showed progressive disease.

The drug, Reolysin, was used intravenously in combination with chemotherapy drugs carboplatin and paclitaxel on patients with squamous cell lung cancer.

The U.S. mid-stage trial was divided into two parts. The first part of a mid-stage trial had earlier met the main goal of showing patient response.

"Based on the positive data seen to date, we intend to conduct further studies in this indication," Chief Executive Brad Thompson said.

The secondary objectives of the trial, for which data is yet to be released, includes assessment of progression-free survival and overall survival for the treatment regimen in the study population, the company said.

(Reporting by Bhaswati Mukhopadhyay in Bangalore; Editing by Saumyadeb Chakrabarty)

Source: http://news.yahoo.com/oncolytics-lung-cancer-drug-effective-mid-stage-trial-142310041.html

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5 Ways Direct Mail Shines in Multichannel Marketing : Page 1 of 2 ...

Marketing campaigns that use a multichannel approach are more effective at reaching audiences and increasing sales, according to ExactTarget's "Subscribers, Fans & Followers Report #14: The 2012 Channel Preference Survey." Of the common marketing channels, direct mail has certain advantages over the rest that can make it the most important channel in your marketing mix. Below are five tactics that small business owners can leverage to get the most out of their direct mail campaigns.

1. Test the Message

Perhaps the greatest benefit of direct mail as a marketing channel is the ability to experiment with the message. It's easy to test different approaches because they aren't expensive to produce compared to other forms of marketing where it often becomes costly to make even minor alterations. After all, sometimes all it takes is a little tweaking to get the results you want.

2. Maximize Versatility
Your direct mail campaign can help you accomplish multiple goals. Consumers can easily read your ad over and over again, which means you can include information about your marketing efforts on other channels. Tell consumers about your website, Facebook page, or invite then to subscribe to your newsletter. Direct mail doesn't just drive sales with offers; it can also help you deepen your relationship with your consumers.

3. Be Relevant and Timely
With more expensive marketing channels, it's not always possible to create multiple versions that you can use throughout the year. However, it's easy to build ongoing direct mail campaigns that deliver timely messages with higher response rates. Use this advantage to deliver specific messages built around seasons, events or whatever else you need.

4. Offer Incentives
This may be the oldest trick in the book, but it's no secret that consumers like discounts. With the large format direct mail pieces available, you can include multiple offers that promote different products. Set as few restrictions as possible to make it easy for consumers to come in and redeem the offer.

5. Connect With Young Consumers
With all the buzz about today's youth being captivated by technology, some people might assume that young consumers would consider direct mail outdated. However, recent studies have found that direct mail is often more successful with younger audiences because they are overloaded by emails. The feeling of a physical piece of mail stands out and cuts through online clutter. In fact, according to the ExactTarget 2012 channel preference survey, 57 percent of 25 to 34 year-olds have made a purchase as a result of a direct mail offer.

Source: http://www.targetmarketingmag.com/article/5-ways-direct-mail-shines-multichannel-marketing/1

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5 Eco-friendly kitchen improvements we can all afford

By Ryan Hirst | March 28, 2013 | DIY, How To's and Guides, Featured Stories, Kitchen Knowledge

A huge amount of emphasis is now on becoming more energy efficient and environmentally friendly within the home. We need to do all we can to ensure electricity bills and energy bills drop too. Having these added incentives give us a reason to improve our home.

Now the ?Green Deal? is in full flow in the United Kingdom we should be looking to improve our home in any way we can ? the kitchen is somewhere we should be doing this in. In today?s article I will give you 5 Eco-friendly kitchen improvements we can all afford, that will not only help to reduce our carbon footprint but also help decrease our bills too.

Recycling and separating waste

This technique will not actually save you any money however it won?t cost you anything either. Instead of having to install anything or change the look of your home, or even have renovations. We can all do this one, no matter where we live in the UK we will be all very familiar with the colour coded recycling bins for different waste products. Spending a little bit of time to separate your waste and dispose of it correctly will contribute to your community hitting local recycling targets and reduce the amount of waste across the county.

By simply taking the time to separate things such as cardboard, paper, waste food and all sorts of other items will contribute nationally and locally to a better environment. One good tip for reusing your waste is to create your own compost heap with your food waste; this can take around 6 months before use but is a good idea if you?re a keen gardener.

Making kitchen repairs

In the kitchen and any other part of the home, one of the main reasons for waste on energy bills is because repairs have not been made. Your homes energy bills and water bills can be higher than they need to be if you have problems such as leaks in the kitchen. This is one for the DIY lover, a good chance to save some money without spending either.

By simply getting the correct sized wrench you can adjust pipes to ensure you are not wasting any water. Another common problem can be windows not being sealed properly allowing heat to leave your home and also the cold to enter? Checking for any cracks and resealing can save money on heating bills.

You may also have waste pipes from your ovens or sinks, if so you need to ensure the holes are properly sealed for the same reasons.

Installing energy saving light bulbs

This is something that hopefully most home owners are already doing. However if you are not I cannot understand why. Do you know how much better an energy efficient light bulb is then the standard one?

In fact an energy efficient light bulb lasts as long as ten years longer and along with this also uses between 70%-75% less energy in its lifetime. So in reality we are not having to change the bulb nearly as many times, which is saving us money but we?re also ensuring that we are becoming more energy efficient in the home and the kitchen. This is something I would definitely advise you doing in the kitchen because of the amount of time being spent in it. We need to save as much money on energy bills as we possibly can.

Energy saving kitchen appliances

The kitchen is probably the most packed room in the home, filled with different appliances, using both electricity and also water. With this in mind we need to think about how we are using them. When it comes to actually replacing appliances or redesigning your kitchen look for ones with the highest possible energy efficiency rating. They are usually around the same price and will save you a lot of money in the long run, what more could you ask for?

There are many appliances you can buy that are energy efficient such as:

-????????? Washing machines

-????????? Dishwasher

-????????? Tumble drier

-????????? Ovens

-????????? Taps etc.

The way we use these appliances contributes to your carbon footprint too. In fact by simply turning your washing machine down onto a 30?C instead of its usual will help save money, think about filling the dishwasher fully before use too.

Is your home properly insulated?

The ?Green Deal? something I have wrote about on many different occasions. Something that I think is a great idea by the government, as I touched on before it is now up and running in the UK. The Green Deal allows us to make energy efficient home improvements, without having to pay it all off in one go.

Although ensuring your home is properly insulated is not just a kitchen improvement it is one that I feel I still have to mention. By properly insulating your home you could be saving as much as 10% on your energy bills annually. So why wouldn?t you want to do so? This is one of the many improvements we can have done to our home from the Green Deal and I urge you all to check it out now.

If you enjoyed this post, please take a moment to share it with your friends and colleagues using your favourite social network.

Source: http://www.eurofitdirect.co.uk/blog/5-eco-friendly-kitchen-improvements-we-can-all-afford/?utm_source=rss&utm_medium=rss&utm_campaign=5-eco-friendly-kitchen-improvements-we-can-all-afford

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Man pleads not guilty to extorting A&M professor

HOUSTON (AP) ? James Arnt Aune was regarded as a fine scholar, mentor and friend by students and his fellow professors at Texas A&M University, where he headed the school's Department of Communication.

But Aune, who jumped to his death from the roof of a campus parking garage in January, battled depression in recent years. He struggled with the administrative duties of being a department head, and he was badly shaken by his 2007 battle with prostate cancer, which he survived but which forced him to face his own mortality, his widow said.

"He never really came all the way back," Miriam Aune said of his surviving cancer.

He began drinking heavily, and in December he started a sexually explicit online relationship with what he thought was an underage girl, according to prosecutors. He was soon contacted by a man purporting to be her outraged father, who threatened to expose Aune unless he paid him $5,000.

Aune paid the man $1,500, but he didn't know if he could come up with the rest, authorities say. He confessed to his wife, who pledged to stand by him, but about a week later, the 59-year-old Aune jumped to his death after sending a final text: "Killing myself now. And u will be prosecuted for black mail."

The man who got that text, according to prosecutors, pleaded not guilty Tuesday in a Houston federal courtroom to an extortion charge. The 37-year-old Metairie, La., resident was ordered to remain in jail without bail, and his trial is scheduled for May 28. If convicted, he faces up to two years in jail. His court-appointed attorney, Marjorie Meyers, declined to comment about the case.

Authorities allege that Aune was one of many victims of a scheme in which the man used his daughter to lure men into sexually explicit online relationships and later blackmailed them. The Associated Press isn't naming the man to protect the identity of his daughter.

In the criminal complaint, prosecutors contend that the man's daughter told authorities in Louisiana in 2011 that her father took naked photos and videos of her and used them "to scam men" through MocoSpace, a social networking website mainly for mobile devices.

On the site, "she would meet men, get their phone numbers and send them pictures and videos then (her father) would call them and say how she was his daughter and how she would need counseling and they had to pay for it."

At the time of that 2011 interview, her father was facing two counts of oral sexual battery and two counts of aggravated incest. The charges were dropped in February 2012 due to a lack of corroborating evidence, said Rachael Domiano, a spokeswoman for the 21st Judicial District Attorney's Office in Louisiana.

Federal prosecutors on Tuesday declined to comment about certain details of the alleged scheme, and it wasn't clear from the criminal complaint if prosecutors believe the defendant's daughter actually interacted with Aune, or if her image was used to allegedly dupe him.

Miriam Aune, 56, told The Associated Press that investigators told her that the defendant was the person who communicated with her husband and other men, pretending to be his daughter. She said her husband told her he began the online chats sometime in December and that by the third or fourth day after the chats began, the defendant reached out to him asking for money.

According to court records, undated texts show Aune scrambling to put money on prepaid credit cards for the defendant and asking for his forgiveness, saying "I am very sorry. It was a weak moment."

A week before his suicide, James Aune confessed to his wife. Miriam Aune said her husband never told her why he did it.

She pledged her support for him, but said he became despondent after his confession.

"I was just telling him there was nothing that we couldn't get through. We have two autistic children we have raised to adulthood. We've been through rough stuff. I thought we could get through this," Miriam Aune said.

According to a criminal complaint, the defendant continued bombarding Aune with profanity laced emails, texts and voicemails, including a Jan. 7 email in which he warned Aune that he had until noon the next day to pay or else "the police, your place of employment, students, ALL OVER THE INTERNET ...ALL OF THEM will be able to see your conversations, texts, pictures you sent ...."

On Jan. 8 at 9:21 a.m., the defendant texted, "3 more hours. If i don't hear from you the calls start," according the criminal complaint by FBI agent Nikki Allen.

At 10:29 a.m., Aune replied, "Killing myself now And u will be prosecuted for black mail."

He jumped from the parking garage roof about a minute later, shocking the A&M campus, which is about 100 miles northwest of Houston.

Miriam Aune doesn't excuse her husband's actions. She said it was his decision to go online and begin the conversations.

"It just shows you anybody can slip off the path. I know a lot of people are very surprised by this. He was very human with flaws, just like all of us," she said.

But she said it saddens her to know that some people will only remember her husband for what happened at the end of his life.

"To him, being a professor, it was a sacred duty to him. And he cared so much about his students," she said as she cried. "The people who know him, who loved him, they are not going to feel any differently about him."

Source: http://news.yahoo.com/man-pleads-not-guilty-extorting-m-professor-004902354.html

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Engineers enable 'bulk' silicon to emit visible light for the first time

Mar. 27, 2013 ? Electronic computing speeds are brushing up against limits imposed by the laws of physics. Photonic computing, where photons replace comparatively slow electrons in representing information, could surpass those limitations, but the components of such computers require semiconductors that can emit light.

Now, research from the University of Pennsylvania has enabled "bulk" silicon to emit broad-spectrum, visible light for the first time, opening the possibility of using the element in devices that have both electronic and photonic components.

The research was conducted by associate professor Ritesh Agarwal, postdoctoral fellow Chang-Hee Cho and graduate students Carlos O. Aspetti and Joohee Park, all of the Department of Materials Science and Engineering in Penn's School of Engineering and Applied Science.

Their work was published in Nature Photonics.

Certain semiconductors, when imparted with energy, in turn emit light; they directly produce photons, instead of producing heat. This phenomenon is commonplace and used in light-emitting diodes, or LEDs, which are ubiquitous in traffic signals, new types of light bulbs, computer displays and other electronic and optoelectronic devices. Getting the desired photonic properties often means finding the right semiconducting material. Agarwal's group produced the first ever all-optical switch out of cadmium sulfide nanowires, for example.

Semiconducting materials -- especially silicon -- form the backbone of modern electronics and computing, but, unfortunately, silicon is an especially poor emitter of light. It belongs to a group of semiconducting materials, which turns added energy into heat. This makes integrating electronic and photonic circuits a challenge; materials with desirable photonic properties, such as cadmium sulfide, tend to have poor electrical properties and vice versa and are not compatible with silicon-based electronic devices.

"The problem is that electronic devices are made of silicon and photonic devices are typically not," Agarwal said. "Silicon doesn't emit light and the materials that do aren't necessarily the best materials for making electronic devices."

With silicon entrenched as the material of choice for the electronics industry, augmenting its optical properties so it could be integrated into photonic circuitry would make consumer-level applications of the technology more feasible.

"People have tried to solve this problem by doping silicon with other materials, but the light emission is then in the very long wavelength range, so it's not visible and not very efficient and can degrade its electronic properties," Agarwal said. "Another approach is to make silicon devices that are very small, five nanometers in diameter or less. At that size you have quantum confinement effects, which allows the device to emit light, but making electrical connections at that scale isn't currently feasible, and the electrical conductivity would be very low."

To get elemental, "bulk" silicon to emit light, Agarwal's team drew upon previous research they had conducted on plasmonic cavities. In that earlier work, the researchers wrapped a cadmium sulfide nanowire first in a layer of silicon dioxide, essentially glass, and then in a layer of silver. The silver coating supports what are known as surface plasmons, waves that are a combination of oscillating metal electrons and of light. These surface plasmons are highly confined to the surface where the silicon dioxide and silver layers meet. For certain nanowire sizes, the silver coating creates pockets of resonance and hence highly confined electromagnetic fields -- in other words, light -- within the nanostructure.

Normally, after excitation the semiconductor must first "cool down," releasing energy as heat, before "jumping" back to the ground state and finally releasing the remaining energy as light. The Penn team's semiconductor nanowires coupled with plasmonic nanocavities, however, can jump directly from a high-energy excited state to the ground state, all but eliminating the heat-releasing cool-down period. This ultra-fast emission time opens the possibility of producing light from semiconductors such as silicon that might otherwise only produce heat.

"If we can make the carriers recombine immediately," Agarwal said, "then we can produce light in silicon."

In their latest work, the group wrapped pure silicon nanowires in a similar fashion, first with a coating of glass and then one of silver. In this case, however, the silver did not wrap completely around the wire as the researchers first mounted the glass-coated silicon on a sperate pane of glass. Tucking under the curve of the wire but unable to go between it and the glass substrate, the silver coating took on the shape of the greek letter omega -- ? -- while still acting as a plasmonic cavity.

Critically, the transparent bottom of the omega allowed the researchers to impart energy to the semiconductor with a laser and then examine the light silicon emitted.

Even though the silicon nanowire is excited at a single energy level, which corresponds to the wavelength of the blue laser, it produces white light that spans the visible spectrum. This translates into a broad bandwidth for possible operation in a photonic or optoelectronic device. In the future, it should also be possible to excite these silicon nanowires electrically.

"If you can make the silicon emit light itself, you don't have to have an external light source on the chip," Agarwal said. "We could excite the silicon electrically and get the same effect, and we can make it work with wires from 20 to 100 nanometers in diameter, so it's very compatible in terms of length scale with current electronics."

The research was supported by the U.S. Army Research Office and the National Institutes of Health.

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The above story is reprinted from materials provided by University of Pennsylvania.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. Chang-Hee Cho, Carlos O. Aspetti, Joohee Park, Ritesh Agarwal. Silicon coupled with plasmon nanocavities generates bright visible hot luminescence. Nature Photonics, 2013; 7 (4): 285 DOI: 10.1038/nphoton.2013.25

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/U1h28iUkbn4/130327133517.htm

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Live donkey helps church observe Palm Sunday

FAIRFIELD -- The children sat cross-legged in the front of the First Presbyterian Church Sunday morning holding palm branches close to their chests.

"Are these palms real?" asked one little boy, just minutes before the children headed to Sunday school to learn about Palm Sunday, the day Jesus rode into Jerusalem on a donkey and was welcomed by people waving palm branches.

Indeed, the palms were real. But it wasn't until the children were seated in class that they learned about the day's big surprise -- a live donkey would soon arrive on the church's front lawn.

After that, "it was so hard to keep their attention through the whole class," said teacher Kim Louise Spinosa, laughing.

As soon as the children were led outside, the palms were given to parents so Jessie, a 20-year-old donkey from JC's Pony Parties in Seymour, wouldn't confuse them for food.

"I feel like the donkey is going to chase me," said one middle-schooler, as Jessie lazily swung its head his way.

"I like it," declared kindergartner Audrey Anderson, who needed little prompting to remember who rode the donkey in the day's gospel readings.

"Jesus," she said, beaming.

Peti Deer, 14, said he didn't expect to be chosen to dress up as one of the disciples sent by Jesus to get the donkey he would later ride into Jerusalem.

"It was a good surprise," Peti said. "You have a real sense of what it was like."

Parishioner Jen Richard's eyes grew wide as Beth Brooks, Jessie's handler, informed the group that donkeys have dark hair on their backs shaped like a cross.

"I think it's fabulous," said Richard, a Fairfield resident. "It just strikes me that the donkey is so meek and mild. I didn't know there was a cross on the back of every one. It makes it seem more real."

Her son, James, who finished reading the Old Testament in his children's Bible recently, was excited to touch and take pictures with Jessie, "especially on Palm Sunday because that's when Jesus rode to town on a donkey."

The 10-year-old's younger siblings, meanwhile, preferred to stay inside the church.

"They want nothing to do with the donkey," said their father, Jeff Richard.

The Rev. Edward Duffy said the church has brought donkeys to Palm Sunday services in the past and would like to make it an annual tradition.

"We've been trying to do it every year, but it's not the easiest thing to find a donkey," Duffy said, noting that it took several tries to find a local farm with a donkey.

"Can you picture Jesus riding on one of these?" Carol Fraser, of Fairfield, asked those gathered around Jessie.

"They are so sturdy and so strong," Brooks said. "I absolutely could."

ktorres@ctpost.com, 203-330-6321, http://facebook.com/ktorresbpt or http://twitter.com/ktorresbpt

Source: http://www.ctpost.com/local/article/Live-donkey-helps-church-observe-Palm-Sunday-4380596.php

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Women Launch Clothing Line for Breast Cancer Survivors

They say necessity is the mother of invention, and in Laurel Kamen's case, it certainly was.

After being diagnosed with breast cancer in September 2011, Kamen underwent a mastectomy. On the eve of her surgery, after trying and failing to find clothes that would be both comfortable and fashionable during her post-operation recovery period, Kamen noticed a gaping hole in the fashion market and decided to fill the niche herself.

Thirteen months later, Kamen is debuting the Alloro Collection, a fashion friendly line of clothing suited for post-op recovery.

"I didn't want to have to step out of the world of fashion just because I had breast cancer," Kamen said. "I wanted to stay in the world of fashion, still be able to buy a nice dress to go out to dinner, or a nice blouse to go to a Bat Mitzvah or a wedding. I just felt that women with all of these sensitivities need to be addressed, and they could still look gorgeous."

The Alloro line is part of a growing movement to accommodate breast cancer survivors. Just last month, Victoria's Secret responded to a Change.org petition asking for a line of "survivor" mastectomy bras, and Nordstrom department stores offer a service that will convert any basic bra or camisole into a mastectomy bra. Related: Daughter Petitions Victoria's Secret for Post-Mastectomy Bras

Kamen and her business partner and best friend Christine Irvin considered the effects of breast cancer treatment on a woman's body, taking into account the change in neckline, color pallor and sensitivity.

"We started looking at what we could do to really help a woman get beautiful back in her life and recapturing the color that cancer had drained from her life," Irvin said.

Their debut collection is made up of 14 original pieces, all of which will be sold entirely online and through trunk shows.

For Kamen, a former American Express executive, and Irvin, a Wall Street veteran, this is quite the change of pace.

"We can both laugh. We can both say that we've been fashion followers," explained Irvin. "We've switched from reading the Wall Street Journal first to reading Vogue first."

When asked what's next for this dynamic duo, Kamen was quick to point out that this is just the beginning for Alloro. "This is all new to us and we just want to go slowly and get it right and connect with women," she said.

One thing's for sure, the clothes don't make the woman. The woman makes the clothes.

Twenty-five percent of all proceeds from the Alloro Collection will be donated to the Breast Cancer Foundation.

Also Read

Source: http://news.yahoo.com/women-launch-clothing-line-breast-cancer-survivors-040001991--abc-news-wellness.html

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Desperate NBC Using Paterno Apologist?s Footage For Sandusky ?Exclusive? Interview (OliverWillisLikeKryptoniteToStupid)

Share With Friends: | | Politics - Top Stories News, RSS and RSS Feed via Feedzilla.

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Winning $338M Powerball jackpot ticket sold in NJ

DES MOINES, Iowa (AP) ? A single ticket sold in New Jersey matched all six numbers in Saturday night's drawing for the $338.3 million Powerball jackpot, lottery officials said. It was the 13th drawing held in the days since a Virginia man won a $217 million jackpot Feb. 6.

Thirteen other tickets worth $1 million each matched all but the final Powerball number on Saturday night. Those tickets were sold in New Jersey and 10 other states. Lottery officials said there was also one Power Play Match 5 winner in Iowa.

The New Jersey Lottery said Sunday that details about the winning ticket would be released Monday, declining to reveal where it had been purchased and whether anyone had immediately come forward. It was the sixth largest jackpot in history.

The numbers drawn were 17, 29, 31, 52, 53 and Powerball 31. A lump sum payout would be $221 million.

Lottery officials said the 13 tickets worth $1 million apiece ? matching the first five numbers but missing the Powerball ? were sold in Arizona, Florida (2), Illinois, Minnesota, North Carolina, New Jersey, New York, Ohio, Pennsylvania (2), South Carolina and Virginia.

Powerball said on its website that the grand prize jackpot has now been reset to an estimated $40 million or a lump sum cash amount estimated at $25 million for Wednesday's next drawing.

No one had won the Powerball jackpot since early February, when Dave Honeywell in Virginia bought the winning ticket and elected a cash lump sum for his $217 million jackpot.

The largest Powerball jackpot ever came in at $587.5 million in November. The winning numbers were picked on two different tickets ? one by a couple in Missouri and the other by an Arizona man ? and the jackpot was split.

Nebraska still holds the record for the largest Powerball jackpot won on a single ticket ? $365 million. That jackpot was won by eight workers at a Lincoln, Neb., meatpacking plant in February 2006.

Powerball is played in 42 states, Washington, D.C., and the U.S. Virgin Islands. The chance of matching all five numbers and the Powerball number is about 1 in 175 million.

Powerball said on its website that the game is played every Wednesday and Saturday night when five white balls are drawn from a drum of 59 balls and one red ball is picked from a drum with 35 red balls. It added that winners of the Powerball jackpot can elect to be paid out over 29 years at a percentage set by the game's rules ? or in a lump sum cash payment.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-03-24-Powerball%20Jackpot/id-cc2c402ea0254ab1a2b71587e26cda10

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'Real World' Star David 'Puck' Rainey Looks Back On San Francisco -- Unapologetically

MTV News chats with 'RW' bad boy before 'RetroMTV' marathon tonight at 8 p.m. ET/PT and Portland premiere next Wednesday.
By James Montgomery, with reporting by Vanessa White Wolf‬

David "Puck" Rainey in 1994
Photo:

Source: http://www.mtv.com/news/articles/1704192/real-world-san-francisco-puck.jhtml

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Legal Challenge Already Planned To Gun Control Laws ? CBS ...

Gov. Hickenlooper signs gun control bills into law on Wednesday. (credit: CBS)

DENVER (CBS4)- There are already legal challenges being planned to two of the gun control bills signed into law by Gov. John Hickenlooper on Wednesday.

The lead plaintiffs are sheriffs from around Colorado. They claim the laws violate not only the Second Amendment, the right to keep and bear arms. but the 14th Amendment which requires laws to be easy to understand.

Even Hickenlooper felt the need to clarify the language after he signed the bills into law.

?Any highly contentious bill is never going to be perfect,? said Hickenlooper.

He released a so-called signing statement.

?What we wanted to do is just provide a little clarity,? said Hickenlooper.

That is something many sheriffs around Colorado believe is missing from the laws.

?The governor refused to meet with them, the legislature ignored them so their claims now will be heard in federal court,? said Independence Institute spokesman Dave Kopel.

Kopel is a constitutional law expert at the Independence Institute. He said the sheriffs are filing a lawsuit to block the laws that they argue are unconstitutional.

Kopel said the Second Amendment prohibits the government from outlawing commonly-owned firearms and accessories like the magazines banned under the new law.

?Even if there were no specific constitutional rights involved, as is here with the right to keep and bear arms, laws on anything must at least pass the rational basis test,? said Kopel.

Kopel said the 14th Amendment requires statutes to be rational and clear so that they can be enforced fairly.

?And as the sheriffs have repeatedly said these laws are not enforceable,? said Kopel.

Kopel said Hickenlooper knows it because his staff called the Independence Institute hours before the signing for ?clarity.?

?In a way his signing statement where he tries to fix the defective statute underscores the defectiveness of the statute,? said Kopel.

Hickenlooper released his signing statement Wednesday afternoon. He said in signing the magazine bill he acknowledges there are concerns about the vagueness of some parts of it.

Hickenlooper also said he has directed the Department of Public Safety to consult with the Attorney General about how to interpret the law and then issue guidance on how to enforce it to police and sheriffs throughout the state.

Source: http://denver.cbslocal.com/2013/03/20/legal-challenge-already-planned-to-gun-control-laws/

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Stem cells use signal orientation to guide division, study shows

Mar. 21, 2013 ? Cells in the body need to be acutely aware of their surroundings. A signal from one direction may cause a cell to react in a very different way than if it had come from another direction. Unfortunately for researchers, such vital directional cues are lost when cells are removed from their natural environment to grow in an artificial broth of nutrients and growth factors.

Now, researchers at the Stanford University School of Medicine and the Howard Hughes Medical Institute have devised a way to mimic in the laboratory the spatially oriented signaling that cells normally experience.

Using the technique, they've found that the location of a "divide now" signal on the membrane of a human embryonic stem cell governs where in that cell the plane of division occurs. It also determines which of two daughter cells remains a stem cell and which will become a progenitor cell to replace or repair damaged tissue.

The research offers an unprecedented, real-time glimpse into the intimate world of a single stem cell as it decides when and how to divide, and what its daughter cells should become. But the implications stretch beyond stem cells.

"In the body, it is likely that every cell grows and differentiates in some kind of orientation," said Roeland Nusse, PhD, professor of developmental biology. "Without this guidance, specialized cells would end up in the wrong place. Now, we can study the division of single mammalian cells in real time and see them dividing and differentiating in an oriented way."

Understanding this process of self-renewal and specialization (or differentiation) is critical to learning how to truly harness the power of stem cells for future therapies. But polarity, or the ability of a cell to distinguish its top from bottom or left from right, is also vital to many other biological processes. For example, hair grows out of, rather than into, the body, and tissues develop with orderly layers of specific cell types.

Nusse is the senior author of the work, published March 23 in Science. He is also a member of the Stanford Cancer Institute, the Stanford Institute for Stem Cell Biology and Regenerative Medicine and HHMI investigator. Shukry Habib, PhD, a research associate and Siebel Scholar, is the lead author of the work. The study was funded in part by a grant from the California Institute of Regenerative Medicine.

Stem cells are unique in their ability to both self-renew and to generate progenitor cells that can become many cell types. A single stem cell can divide to make two new stem cells or, in a process called asymmetric division, give rise to one stem cell and one progenitor cell. Because the original parent cell is replaced by the two new daughter cells, this approach ensures that stem cells will not be depleted during periods of development or healing.

Things change when these cells are grown in the laboratory, however. Researchers usually choose growth conditions that favor specific outcomes: self-renewal or differentiation into specialized cell types. These growth or differentiation signals affect all parts of the cell equally, and it's not been possible under these conditions to ascertain whether and how the location of these signals may affect the outcome.

In the current study, Habib tested the effect on human embryonic stem cells of a protein called Wnt3a, which is known to play a critical role in embryonic development and in the growth and maintenance of stem cells. The stem cells have many receptors for Wnt proteins on their surfaces, and Wnt3a has been shown to promote self-renewal over differentiation in several types of stem cells.

Habib attached molecules of Wnt3a protein to tiny synthetic beads and incubated the beads with embryonic stem cells. He then observed the reaction over time of the cells to which a single bead-bound protein had attached via one of the cell's many Wnt3a receptors.

The effect of the localized signal was clear. In 75 percent of cases, the stem cell began to divide in a very specific orientation, with the plane of division occurring perpendicularly to the location of the incoming signal. In contrast, only 12 percent of cells exposed to beads bound to a control protein exhibited similar patterns of division.

Habib and his colleagues also found that the daughter cell closest to the Wnt3a signal expressed proteins showing it was maintaining its pluripotency, or ability to function as a stem cell like its parent. The one farthest from the signal, however, expressed proteins indicating that it was beginning to differentiate.

The researchers speculate that the reduction in the intensity of the Wnt signal in the distant daughter cell is what causes it to begin the differentiation process; the loss of the Wnt3a signal is known to cause cultured stem cells to begin differentiating.

"We found that these two processes, division and differentiation, are coupled," said Nusse, who is also the Virginia and Daniel K. Ludwig Professor in Cancer Research. "In real life, of course, the cell is exposed to many signals simultaneously. But by studying just one protein and just one cell, we can clearly see that the cell's division is aligned to the source of the Wnt signal. One of the daughters is always closer and remains pluripotent. The other is further from that signal; it begins to differentiate."

The researchers would like to extend their studies to other types of stem cells, as well as to cells that have mutations in other components known to affect cell polarity.

Other Stanford co-authors include postdoctoral scholar Feng-Chiao Tsai, MD, PhD, and professor of chemical and systems biology Tobias Meyer, PhD.

The research was funded by the National Institutes of Health, CIRM, HHMI and the Center for Regenerative Therapies in Dresden. Habib and Nusse have applied for a patent on the bead immobilization technique described in the paper, as well as its applications.

Information about the Department of Developmental Biology, which also supported the work, is available at http://devbio.stanford.edu.

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The above story is reprinted from materials provided by Stanford University Medical Center. The original article was written by Krista Conger.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. Shukry J. Habib, Bi-Chang Chen, Feng-Chiao Tsai, Konstantinos Anastassiadis, Tobias Meyer, Eric Betzig, and Roel Nusse. A Localized Wnt Signal Orients Asymmetric Stem Cell Division in Vitro. Science, 2013; 339 (6126): 1445-1448 DOI: 10.1126/science.1231077

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/AImSjUvYnuI/130321141446.htm

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Hillary backs same-sex marriage (CNN)

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Fluorescence Could Indicate Health of Corals

Corals are well-known for the brilliant colors they sport, but less well-known is the light, or fluorescence, that most coral species give off. Monitoring the levels of this fluorescence could be an easier way for scientists to monitor the health of coral reefs around the world, a new study finds, as these reefs are subjected to stress from climate change and other factors.

Coral fluorescence, produced by special fluorescent proteins, is a relatively poorly understood phenomenon, but researchers think it could help protect the coral from damaging sunlight, or possibly other forms of stress.

Marine biologists at the Scripps Institution of Oceanography at UC San Diego monitored the levels of fluorescence and fluorescent proteins in a common branching coral from the Indo-Pacific region called Acropora yongei as the coral was subjected to both cold and heat stress. These stresses both affect corals in nature, with cold snaps sometimes killing corals, and global warming heating up the oceans overall.

Fluorescence levels from the coral in the study declined rapidly in response to both types of stress, initially, but the outcomes of the two tests eventually differed. The coral was able to adapt to the cold temperatures and their fluorescence levels rebounded, but the heat stress caused the corals to bleach, or lose the symbiotic algae that provides corals with the bulk of their nutrition.

Under the heat stress conditions, the fluorescence levels declined at first as they did under the cold stress, but the coral couldn't adapt and the algae were expelled from the corals, study researcher Melissa Roth, now at Lawrence Berkeley National Laboratory and UC Berkeley, told OurAmazingPlanet in an email. When the bleaching happened, there was actually a spike in fluorescence caused by the fact that the algae had previously been shading the fluorescence and now no longer were.

"This is the first study to quantify fluorescence before, during and after stress," said Scripps researcher Dimitri Deheyn in a statement.

The results show that fluorescence can be a good marker of the health of corals. In fact, it could be an easier, less invasive method of monitoring corals than those currently used, including analyzing corals collected from reefs back in labs. Fluorescence can be monitored without disturbing the coral and directly at the reef site, and could indicate that the coral is in poor health before it bleaches. [Video: Humans Hit the Oceans Hard]

Roth said that the coral the study tested, Acropora yongei, would be a good one to monitor in the field because branching corals like it are "very susceptible to bleaching."

"It would make sense to monitor the corals on the reef that are most sensitive as an indicator for the reef as a whole," Roth said.

The findings were detailed in the March 12 issue of the journal Scientific Reports.

Follow Andrea Thompson @AndreaTOAP, Pinterestand Google+. Follow OurAmazingPlanet?@OAPlanet, Facebook?and Google+. Original article at LiveScience's OurAmazingPlanet.

Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://news.yahoo.com/fluorescence-could-indicate-health-corals-180133660.html

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Oceanside chamber honors military heroes

Oceanside Chamber of Commerce President David L Nydegger with Brig. Gen. Vincent A. Coglainese. CREDIT: Randel Berg

Honorees plaques and certificates at the Oceanside Chamber's Enlisted Recognition Dinner on Feb. 22. CREDIT: Randel Berg

Oceanside Deputy Mayor Jack Feller, City Councilwoman Farrah Douglas, honoree Sgt. Juan Moreno and Brig. Gen. Vincent Coglianese at the Oceanside Chamber's Enlisted Recognition Dinner on Feb. 22. CREDIT: Randel Berg

Sgt Christopher Luckert, Spouse of the Year winner Sarah Luckert, Len Santivasci of USA Discounters and Brig. Gen. Vincent Coglainese. CREDIT: Randel Berg

Honorees Sgt. James Armstrong and Cpl. Tessa Sisk. CREDIT: Randel Berg

Spouse of the Year finalists Trish Jones, Sarah Luckert and Stacie Black with Len Santivasci of USA Discounters. CREDIT: Randel Berg

Honoree HM2 Aimee Granger with Brig. Gen. Vincent Coglianese. CREDIT: Randel Berg

Oceanside City Councilwoman Farrah Douglas with Sgt Jose Nunez and Brig. Gen. Vincent Coglianese. CREDIT: Randel Berg

Oceanside ? For 71 years, the city of Oceanside and its next door neighbor, the Marine Corps Base Camp Pendleton, have had a close and mutually beneficial relationship.

To thank its military neighbor to the north, the Oceanside Chamber of Commerce Foundation held its third annual Enlisted Recognition Dinner on Feb. 22. The gala allows Oceanside?s business community to pay tribute to the base?s top marines and sailors, as well as their wives.

More than 150 attended the dinner at the El Camino Country Club. The honorees and their guests were treated to dinner and received plaques, certificates and other gifts.

The evening?s festivities included a speech by Brigadier General Vincent A. Coglianese, who is commanding general for Marine Corps Installations West and commander of Marine Corps Base Camp Pendleton. And City Councilmembers Jack Feller and Farrah Douglas were in attendance. But the true stars of the night were the men and women who were honored. This included 17 military service members and three spouses.

Honorees were Cpl. Andrew M. Bierach, named Noncommissioned Officer of the Year; Cpl. Brandon E. Wayne, Marine of the Quarter; Sgt. Jose Nunez, Noncommisioned Officer of the Year; Sgt. Maxmillion Page, Noncommisioned Officer of the Year; Cpl. Tessa R. Sisk, Marine of the Year; Sgt. Delando A. Bradford, Noncommissioned Officer of the Year; HM2 Aimee J. Granger, Sailor of the Year; Sgt. James M. Armstrong, Noncommissioned Officer of the Year; HM2 Aaron R. Belcher, Junior Sailor of the Year; HM1 Aaron L. Giacoletti, Sailor of the Year; Sgt. Juan C. Moreno, Noncommissioned Officer of the Year; HN Thomas B. Arnold, Blue Jacket of the Year; YN3 Damien S. Harper, Junior Sailor of the Year; BM3 Siera Q. Coffee, Junior Sailor of the Year; Lance Cpl. Nydia Garcia, Marine of the Quarter; Cpl. Bilma J. Diaz, Noncommissioned Officer of the Year.

There were also three finalists for the Spouse of the Year Award: Sarah Luckert, Trish Jones and 1st Sgt. Stacie Black. The winner, Luckert, received a diamond necklace, and all three women received gift baskets from USA Discounters.

The gala was organized by event emcee Chip Dykes, who is chair of the chamber?s Military Affairs Committee, and David L. Nydegger, president and CEO of the chamber.

The event?s co-sponsors were Pacific Marine Credit Union and Navy Federal Credit Union. Table sponsors included Tri-City Medical Center, Mossy Nissan Oceanside, Southern California Edison, Nitto Denko Hydranautics, San Diego Gas & Electric, Waste Management of North County and Pioneer Services.

More than $6,5000 was netted at the event. Proceeds will go toward several military-themed events the Chamber hosts throughout the year, including Operation Appreciation and Golf with a Hero, as well as educational scholarships and classroom grants, according to Kristi Hawthorne, event coordinator for the chamber.

Source: http://www.utsandiego.com/news/2013/mar/17/chamber-hosts-gala-for-military/

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Former Miami State Senator Larcenia Bullard Dies

The Miami Herald:

Former state Sen. Larcenia Bullard was the rarest of politicians in the state Capitol: She seemed to make everyone happy and had no apparent enemies.

Read the whole story at The Miami Herald

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Former state Sen. Larcenia Bullard was the rarest of politicians in the state Capitol: She seemed to make everyone happy and had no apparent enemies.

Former state Sen. Larcenia Bullard was the rarest of politicians in the state Capitol: She seemed to make everyone happy and had no apparent enemies.

Filed by Janie Campbell ?|?

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1. HuffPost
2. Miami

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Source: http://www.huffingtonpost.com/2013/03/17/former-miami-state-senato_n_2895393.html

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Saint Louis beats VCU 62-56 to win A-10 tourney

Virginia Commonwealth's Darius Theus, center, jumps through Saint Louis defenders Kwamain Mitchell, left, and Mike McCall Jr. during the first half of an NCAA college basketball game in the championships of the Atlantic 10 Conference tournament on Sunday, March 17, 2013, in New York.

Virginia Commonwealth's Darius Theus, center, jumps through Saint Louis defenders Kwamain Mitchell, left, and Mike McCall Jr. during the first half of an NCAA college basketball game in the championships of the Atlantic 10 Conference tournament on Sunday, March 17, 2013, in New York.

Saint Louis' Kwamain Mitchell, left, shoots over Virginia Commonwealth's Rob Brandenberg during the first half of an NCAA college basketball game in the championships of the Atlantic 10 Conference tournament, Sunday March 17, 2013, in New York.

NEW YORK (AP) ? Saint Louis interim coach Jim Crews won't say the Billikens won this championship for the late Rick Majerus. Some things are bigger than basketball, and Crews' respect for Majerus is one of them.

Still, he sees his predecessor's imprints on all the little things his veteran players did right in beating VCU in the Atlantic 10 title game. Their hard-nosed style that left the Rams in foul trouble. Their disciplined defense. Their poise when momentum and a hostile crowd went against them.

No. 16 Saint Louis won just its second conference tournament title in school history Sunday, beating the 25th-ranked Rams 62-56. Kwamain Mitchell, whose senior season started 11 games late because of foot surgery, scored 19 points, including a huge 3-pointer with the shot clock winding down.

"Losing one of the best coaches in NCAA basketball, all those things brought us together," Mitchell said. "All those hard times, it paid off right now. I'm just excited guys stuck with it."

Top-seeded Saint Louis (27-6) led 45-32 with less than 12 minutes left; VCU was in all sorts of foul trouble. But the second-seeded Rams and their pressing defense can erase a deficit as quickly as any team in the country, and VCU (26-8) was within a point three minutes later.

"We weren't worried they were only a point behind," senior forward Cody Ellis said. "The boys did a great job of keeping their composure. It was unreal."

Ellis, who shot just 3 for 10 overall, hit a 3-pointer on the Billikens' next possession, then made another clutch 3 for a 57-51 lead with more than two minutes to go.

Saint Louis had been the best team in the Atlantic 10 all year, led by eight juniors and seniors. Crews reminded his players of how few schools win both the regular-season and conference tournament titles, and that ran through Mitchell's head all game.

Majerus died in December after being hospitalized for several months, and fans chanted his name as the players celebrated the title.

"Rick's footprint and fingerprints, his lessons, are embedded into those guys," Crews said. "His wisdom is embedded into those guys, which is pretty cool."

The Rams, meanwhile, struggled through two scoring droughts of more than five minutes in the first half. When they don't score, they can't set up their press, and Saint Louis didn't commit a turnover for a 16-minute stretch spanning both halves.

But with VCU down 13, Treveon Graham hit a 3-pointer, just the Rams' second of the day, to spark a trademark VCU run. Rob Brandenberg turned a steal into a three-point play in transition, then Briante Weber dished to Juvonte Reddic for a basket in the paint.

When Melvin Johnson, a freshman from the Bronx, made a jumper to pull the Rams within four, he pumped his fist and the crowd erupted as Saint Louis called a timeout.

It did little to calm the Billikens. Saint Louis broke the press but was still visibly flustered, and Mike McCall threw the ball to no one.

Saint Louis committed another turnover on its next possession, and Reddic's dunk in transition pulled VCU within 46-45 with less than nine minutes left.

Graham finished with 20 points and 12 rebounds, while Reddic had 15 points and eight rebounds. But Troy Daniels, who made six 3-pointers to score 20 points in the semifinals against UMass, was held scoreless, missing all four 3-point attempts while limited by foul trouble.

The Rams shot 3 for 18 from behind the arc.

"Our whole style of play is to get the other team rattled, and I think for a stretch there we had it going the way we wanted," VCU coach Shaka Smart said. "They were having trouble even getting the ball inbounds. But then they've got some older guys that stepped up, that made big shots."

Like Ellis, who calmly drained an open 3-pointer after Johnson fell down on defense. He drilled another jumper after Graham's 3 again drew the Rams within a point.

And Mitchell made that 3-pointer with Reddic, nearly a foot taller, draped on him to give Saint Louis a 54-48 lead with more than four minutes left.

There were plenty of empty seats at the Barclays Center in the A-10's first season in Brooklyn. But many who were there wore black and gold, including famous New York City basketball fan Spike Lee, who attended all three of VCU's games and was wearing a Rams jersey Sunday.

When VCU went on its run, its section had the place rocking, even booing Saint Louis cheerleaders.

The Rams were in their first season in the A-10 after winning the Colonial Athletic Association conference tournament title last year.

Saint Louis, also a relative newcomer, was making its first appearance in the A-10 title game after joining in 2005-06. Its only previous conference tournament crown came in 2000 in Conference USA.

Mitchell shot 7 of 9 from the floor. So excited for his team's prospects after Saint Louis won a game in last year's NCAA tournament, Mitchell broke his foot in the second practice of the preseason.

But "he didn't have a pity party," Crews said.

"He has been a pillar with that kind of mentality and attitude," the coach added.

Dwayne Evans scored 16 points after combining for 49 the previous two days and earned tournament MVP honors. The Billikens got to the foul line 33 times but missed 12 free throws to help VCU stick around.

"These guys off the court have had a lot of situations," Crews said. "And certainly on the floor you always have different situations. You're going to have ebb and flows. You're going to not play well. You're going to make a mistake. You're going to have a period of time where things aren't going your way, things you might not even understand off the court or on the court.

"All you can do is try to do the next right thing."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2013-03-17-BKC-T25-A10-VCU-Saint-Louis/id-7de3560cba9b4258bb3ceeeeabdc355f

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